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- ItemDetermination of prothrombin time and activated partial thromboplastin time among diabetic patients attending in Military Hospital in Khartoum state(Napata College, 2022-10)Background: This is a descriptive cross sectional study that conducted in Military Hospital during the period from June, 2022 to October 2022. Aim: detect the variation of Prothrombin Time and Activated Partial Thromboplastin Time between diabetic patient attending Military Hospital for diabetes and healthy individual.50 samples were collected from both genders, 25 samples from diabetic patients in which there were 14 males and 11 females and 25 samples from healthy individuals in which there were 17 males and 8 females. Material and method: In this cross sectional study case control study 25 diabetic patients and 25 healthy individuals were subjected to Prothrombin time(PT), Activated partial thromboplastin time(APTT) and international normalization ratio(INR) patients in the department of hematology, this study conducted in Military Hospital during the period from June to October 2022, Results: the results showed that, the mean of prothrombin time was 15.440 sec in diabetic patients and 17.564 sec in healthy individuals, there is significant difference in PT (P=0.038). The mean of activated partial thromboplastin time was 33.868 sec in diabetic patients and 36.592 sec in healthy individuals, there is insignificant difference in APTT (P=0.336). The mean of INR was 1.7440 sec in diabetic patients and 1.6904 sec in healthy individuals there is insignificant difference in INR (P=0.649). Conclusion: This mean that there is a significant association between Diabetes mellitus and coagulation parameters which may result in increased morbidity and premature mortality of diabetic patient.
- ItemAssessment of Soc ioeconomic And Psychological Impact of Hemodialysis Among Patients With End Stage Renal Disease In Bahri Teaching Hospital From August-December 2022(Napata College, 2022)1.2 Background: End-stage renal failure, also known as end-stage renal disease (ESRD), is the final, permanent stage of chronic kidney disease, where kidney function has declined to the point that the kidneys can no longer function on their own. 1.3 Justification: Renal failure is a common health problem worldwide and dialysis is considered as the most effective replacement therapy. It affects the social quality of life of patients and may lead to some sort of dysfunction. The cost of dialysis in developing countries exceeds the financial ability of the majority of patients also affect their psychologicl health This study aims to assess the socioeconomic and psychological problems that facing dialysis patients and try to find suitable solutions for it as much as possible. 1.4 General objective: Assessment of socioeconomic and psychological impact of end stage Renal disease 1.5 Specific Objectives : -To identify sociodemographic characteristics that affect on end stage Renal disease . -To study the psychological effect of dialysis and related changes. -To assess social impact of dialysis on end stage Renal disease patients. -To compare between income of patient and the cost of hemodialysis. Aim of the study To assess the socio-economic impact and psychological effect of renal dialysis on patients of end stage Renal disease Method A descriptive cross sectional hospital based study was conducted at bahri teaching hospital in Renal Dialysis Center in August 2022 and it included 151 patients with end stage renal disease on dialysis process. All patients were interviewed to collect the socio-demographic and clinical data based designed questionnaire and the collected data was analyzed by statistical package for the social sciences. Result the average age of study population was ( >46) year which represent (52.3%) ,with gender predominance for male (51.7%) , the majority of them were university educated (27.8%) ,about (48.3%) of them were unemployed, (73.5%) married (3.3%) of the participants were divorced due to morbidity , (33.7%) of patients had low economic status while (25.8%) had moderate to high economic status , (42.4%) receive dialysis for ≥ 5 years , (95%) have permanent dialysis ,(53%) their income didn’t cover their cost of dialysis and life demand , (4%) of patients turn to sale their property to deal with the cost of dialysis , other ( 86.1%) receive financial support from their families , (72.8%) of patients their social life affected, ( 27.2%) not affected , from (n=16) of student patients there was ( n=13) left their study while ( n=3) continued their study regularly , (40%) of the patients were depressed while ( 60%) weren’t depressed and the majority of the depressed were female (61.7%). Conclusion Renal dialysis is a life-sustaining treatment for patients with end stage renal disease; however, it adversely affects patients’ social life and psychological status also their economic status was affected negatively in bahri teaching hospital in Renal Care Center because the cost of dialysis exceed their monthly income.
- ItemASSESSMENT OF COAGULATION PROFILE AMONG METHAMPHETAMINE SUDANESE ADULTS ABUSERS IN KHARTOUM STATE(Napata College, 2022-10)Background: Methamphetamine is strong addictive drug that has serious physiological and psychological effects on human; we performed this study to assess the coagulation profile among Methamphetamine Sudanese adult abusers in Khartoum state. Method: An analytical case control study aimed on testing coagulation parameters on methamphetamine abuser as a case group and nonusers as a control group, the recorded results were analyzed using SPSS program. Results: A 50 samples of case group and 50 samples of control group were tested against each other for coagulation tests. The analyzed results revealed that males were abusing methamphetamine were much more than females. The analysis also shows that the addicts who have been abusing meth for a long time have a higher PT, APTT and INR than the patients who using it recently. The platelets of methamphetamine abusers were a bit lower than the people with no history of abusing. Conclusion: The findings suggest that the study populations are at higher risk of coagulopathies. Planning of drug awareness programs and developing of the rehabs centers would help to reduce the effect of Methamphetamine drug.
- ItemDetermination of prothrombin time and activated partial thromboplastin time among diabetic patients attending in Military Hospital in Khartoum state(Napata College, 2022)Background: This is a descriptive cross sectional study that conducted in Military Hospital during the period from June, 2022 to October 2022. Aim: detect the variation of Prothrombin Time and Activated Partial Thromboplastin Time between diabetic patient attending Military Hospital for diabetes and healthy individual.50 samples were collected from both genders, 25 samples from diabetic patients in which there were 14 males and 11 females and 25 samples from healthy individuals in which there were 17 males and 8 females. Material and method: In this cross sectional study case control study 25 diabetic patients and 25 healthy individuals were subjected to Prothrombin time(PT), Activated partial thromboplastin time(APTT) and international normalization ratio(INR) patients in the department of hematology, this study conducted in Military Hospital during the period from June to October 2022, Results: the results showed that, the mean of prothrombin time was 15.440 sec in diabetic patients and 17.564 sec in healthy individuals, there is significant difference in PT (P=0.038). The mean of activated partial thromboplastin time was 33.868 sec in diabetic patients and 36.592 sec in healthy individuals, there is insignificant difference in APTT (P=0.336). The mean of INR was 1.7440 sec in diabetic patients and 1.6904 sec in healthy individuals there is insignificant difference in INR (P=0.649). Conclusion: This mean that there is a significant association between Diabetes mellitus and coagulation parameters which may result in increased morbidity and premature mortality of diabetic patient.
- ItemDetermination PT and APTT in pregnant women in Khartoum during the period from June to October 2022.(Napata College, 2022)As a result of the typical physiological needs of pregnancy and childbirth, the hemostatic system develops a physiological hypercoagulable condition and the levels of coagulation factors I, VII, IX, X and XII rise during pregnancy. The aim of this study was to compare pregnant women to non-pregnant women in terms of coagulation changes during all three trimesters of pregnancy. The research was conducted 50 pregnant women, aged range between 20-39 year, who attended Dar ALelag Medical laboratory in Khartoum-Sudanduring the period from June 2022 to January 2023,followed undone for all 50 pregnant women during (first, second and third trimesters) by assigning PT,& PTT and compared with other 50 non-pregnant women which serve as controls. PT,& PPT showed decrease in third trimesters in pregnant women and PT also decrease in second trimester, while PTT decrease in all three trimesters in pregnant women when compared with non-pregnant women. These parameters also decrease in third trimester when compared with first trimester. In good, a condition of physiological low-grade intravascular coagulation characterizes normal pregnancy. In our research, in each trimester, there were alterations in the levels of coagulation parameters. In addition, the ranges for coagulation measures were supplied, which may help clinicians track coagulation in pregnant women more effectively.