Determination of prothrombin time and activated partial thromboplastin time among diabetic patients attending in Military Hospital in Khartoum state
Determination of prothrombin time and activated partial thromboplastin time among diabetic patients attending in Military Hospital in Khartoum state
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Date
2022
Authors
Hassan Musa Mohammed
Marafi Salah Aldeen Mahjoup
Randa Abdalrahman Ahmed
Rayan Gamal Mohammed
Journal Title
Journal ISSN
Volume Title
Publisher
Napata College
Abstract
Background: This is a descriptive cross sectional study that conducted in Military
Hospital during the period from June, 2022 to October 2022.
Aim: detect the variation of Prothrombin Time and Activated Partial Thromboplastin
Time between diabetic patient attending Military Hospital for diabetes and healthy
individual.50 samples were collected from both genders, 25 samples from diabetic
patients in which there were 14 males and 11 females and 25 samples from healthy
individuals in which there were 17 males and 8 females.
Material and method: In this cross sectional study case control study 25 diabetic
patients and 25 healthy individuals were subjected to Prothrombin time(PT), Activated
partial thromboplastin time(APTT) and international normalization ratio(INR) patients
in the department of hematology, this study conducted in Military Hospital during the
period from June to October 2022,
Results: the results showed that, the mean of prothrombin time was 15.440 sec in
diabetic patients and 17.564 sec in healthy individuals, there is significant difference in
PT (P=0.038). The mean of activated partial thromboplastin time was 33.868 sec in
diabetic patients and 36.592 sec in healthy individuals, there is insignificant difference
in APTT (P=0.336). The mean of INR was 1.7440 sec in diabetic patients and 1.6904 sec
in healthy individuals there is insignificant difference in INR (P=0.649).
Conclusion: This mean that there is a significant association between Diabetes mellitus
and coagulation parameters which may result in increased morbidity and premature
mortality of diabetic patient.