Issue 3

Permanent URI for this collection

http://dspace.napata.edu.sd/handle/123456789/90

Browse

Browsing Issue 3 by Title

Now showing 1 - 7 of 7
  • Item
    Advances in Scientific Research
    (Napata Research and Innovation Center (NARIC), 2022-09-27) Napata First Scientific Conference
  • Item
    Assessment of Nurses’ Knowledge, Attitude and Practice of Oral Hygiene for Intensive Care Unit Patients at seven Governmental Hospital In Khartoum State, Sudan, 2020-2021
    (Napata College, 2022-09-20) Mazin Babiker; Emad Abd alkarim; Amar Nooraldin
    Background: Oral care is a vital procedure for critically ill patients in the intensive care unit (ICU). Oral care may affect the clinical result as well as the wellness of intensive care patients. Adequate knowledge about oral nursing care guidelines is important for nurses to deliver appropriate oral care. Materials & Methods: A descriptive cross sectional hospital based study was conducted aimed to assess knowledge, attitude and practice of intensive care nurses regarding oral care in critically ill patients in seven governmental hospitals in Khartoum State. The sample size consisted of 95 nurses in ICUs. Data were collected using interview questionnaire; data was analyzed using Statistical Package for Social Sciences (SPSS). Results: The results revealed that 65.3% of nurses had 1 to 3 years of experience. Regarding the definition of dental plaque, 63.2% of participants responded with correct answers. Only 4.2% knew that gingivitisisagum disease and 24.2%said that gingivitis is due to plaque. A percentage of 64.2% participants knew that periodontitis is an inflammation of tooth supporting structure, and 24.2% said that plaque is the cause of periodontitis. Regarding the practice of mouth care twice per a day, 57.9% participants do practice it.
  • Item
    Case study: Contributory Factors to In-hospital Maternal Mortality in a Governmental Hospital in Khartoum State in 2006
    (Napata College, 2022-09-24) Christelle Evans; Mutasim El-Feel; Abdelmageed Osman
    Background: In-hospital maternal mortality rates in Sudan are currently high, at 0.09%(1). According to World Health Organisation standards, in-hospital maternal mortality should not exceed 0.025%(2). Common contributory factors are numerous, both in-hospital and in the community. This study aims to identify specific contributors to maternal mortality and morbidity in a governmental hospital to make recommendations to minimize them. Materials and Methods: The study basis was an initial case study of maternal morbidity in a governmental hospital with subsequent exploration of contributory factors. A participatory rapid appraisal approach was used, employing observational checklists and semi-structured interviews in order to identify problems at every level of the hospital system, cross-checking information with different stakeholders. Results: Results identified primary delays in seeking care and suboptimal care delivery as the main contributors to in-hospital maternal mortality and morbidity. Interviews with patients and staff also highlighted a need for more patient education and more supervision and training opportunities for junior staff.
  • Item
    Correlation between Oral Premalignant Lesions and Tobacco Use
    (Napata College, 2022-09-27) Raneem MohammedSalahEldin AbdElgadir; Abrar Ahmed Alyayeb; Afra Siddig Mohammed; Alaa Abdallah Abakr1, Hiba Salah FadlAlseed; Hiba Salah FadlAlseed; Ahmed Hashim MohannedSalih Alfaki
    Background: Tobacco use is a major public health problem globally. According to the WHO, tobacco is the second most significant cause of death in the world. Tobacco is used in different forms: smoke and smokeless. The use of tobacco and smokeless tobacco has increased and has associated with oral leukoplakia and other precancerous oral lesions. The presence of leukoplakia in adolescent users of smokeless tobacco is related to years of use, frequency of use, and the amount used. Malignant transformation may occur in 0.5% to 6.2% of individuals and is expected to increase with years of use. Objectives: To identify the correlation between oral premalignant lesions and tobacco use. To study the prevalence of oral premalignant lesions among tobacco using patients. To determine the correlation between tobacco and oral premalignant lesions and the risk of tobacco using and to find out the relation between oral premalignant lesions in tobacco users and gender. Methods: This is an analytical, quantitative systematic review study (known to some as a review article) that was conducted in the Republic of the Sudan by students at the school of dentistry at Napata College. This review is meant to discuss the prevalence of oral premalignant lesions among tobacco users, to assess the association between them and to determine the most found types of oral lesions in tobacco users. To write this paper, we inserted a plethora of keywords associated with the topic at hand. A number of researches were excluded as they were inaccessible to us; unrelated to the topic or because they were relatively anachronistic. Following this, we were left with a total of 13 papers, the findings of which are illustrated here. Results: As an overall, and from the studies mentioned, all studies agreed that thereis a correlation between oral premalignant lesions and tobacco use, in which the prevalenceof oral premalignant lesions found in tobacco using patients was between 48% and 60%. Regarding the most seen types of oral lesions related to tobacco use, the commonest lesions in all studies were found to be leukoplakia, keratosis and oral sub-mucous fibrosis. There was a degree of association found between male tobacco users and oral premalignant lesions in some studies.
  • Item
    Genetic Analysis of TP53 Gene Mutations in Exon 4 and Exon 8 among Esophageal Cancer Patients in Sudan
    (Napata College, 2022-11) Sulafa Mohamed Eltaher; AbeerBabiker Idris; Mahmoud A. H; MawadahYousif Mohamed Yousif; Muzamil M. Abdel Hamid; Kamal Elzaki Elsiddig; Galal Mohammed Yousif; Mohamed A. Hassan
    Background: Esophageal Carcinoma (EC) represents the firstrank among all gastrointestinalcancers in Sudan. There are few publications in which there is an absence of literature about themolecular pathogenesis of EC considering TP53 gene from Sudanese population. Aims: In this study we performed the expression analysis on p53 protein level byimmuno-histochemical staining and examined its overexpression with p53 mutations in exons 4 and 8 among esophageal cancer patients in Sudan. Material and Methods: Fixed tissue with 10% buffered formalin was stained by Hematoxlinand Eosin (H&E), Alcian blue- Periodic Acid Schiff (PAS) and immunohistochemistry stain.PCRRFLP was used to study the frequencies of p53 codon 72 R/P polymorphism. ConventionalPCR and Sanger sequencing were applied for exon 4 and exon 8. Then detection and functionalanalysis of SNPs and mutations were performed using various bioinformatics tools. Results: Nuclear accumulations for p53 protein was detected in all of the esophageal examined carcinomas, while no accumulations were observed in normal control sections. Four patients that were immune-positive for p53 showed no mutations in p53 gene (exon4 and exon8). The incidence ofthe homozygous mutant variant Pro/Pro was higher in esophageal cancerous patients comparingto healthy control subjects 20(71. 4%) vs. 1(10%), respectively (p=0.0026). In exon 4, nomutation was detected other than NG_017013.2:g. 16397C>G. While in exon 8, g.18783-18784AG>TT, g.18803A>C, g.18860A>C, g.18845A>T and g.18863_ 18864 InsT wereobserved. Conclusion: We found a significant association between the overexpression of TP53 protein andmutations in exon 4 and 8. A silent mutation P301P was detected in all of examined cases. Twopatients who were diagnosed with small cell sarcoma shared the same mutations in exon8.Further studies with a larger sample size are required to demonstrate the usefulness of thesemutations in the screening of EC especially SCCE.
  • Item
    Memorial of a Sudanese Scholar Dr. Abd-Allah Eltayeb Abd-Allah (1921-2003)
    (Napata College, 2022) Mohammed Elhassan Altikaena
  • Item
    Pendred Syndrome and Role of Pendrin on Thyroid Physiology
    (Napata College, 2022-10-05) Nada Mukhtar