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Browsing Medical Laboratories by Author "Alkhair Abd Almahmoud Idris"
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- ItemA rare diagnostic case of angioimmunoblastic T-cell lymphoma(Science Progress and Research, 2021-12-22) Mujahed Nooraldaem Mirghani Adam; Mohammed NooraldaemMirghani Adam; Alkhair Abd Almahmoud Idris; Ali Seedahmed Mohamed Ali; Ismail Osman KhalidAngioimmunoblastic T-cell lymphoma is a malignancy of mature T-cells. A 45 years old Sudanese female with generalized lymphadenomegalyreferred from Tayba hospital to Al-tayseer reference medical centre in histopathology and cytology laboratory department (Sudan) for her lymph node histopathology analysis. A surgical lymph node biopsy for histopathology analysis stained by H&E was performed and sections showed effacement of normal architecture of lymph node with disappearance of follicles and germinal center composed of polymorphic infiltrate of small tumour cells and large tumour cells. The small tumour cells showed irregular nuclei and clear cytoplasm. In this case report, we state that the delay of diagnosis was mainly a consequence of an insufficient clinical history, which led to an incomplete histological analysis, delay of reporting and need for second opinions for interpretation.
- ItemAssessment of Sex knowledge and Sexual Education of Sudanese women with Cervical Cancer(International Journal of Academic Pedagogical Research, 2021-08) Alkhair Abd Almahmoud Idris; Alla Hashim SidigThe main objective was to investigate the level of sex knowledge, sexual education of women diagnosed with cervical cancer in Khartoum State. Methods: This descriptive, cross sectional based study has been conducted in Khartoum State. Samples of 200 Sudanese women, 100 of them were diagnosed with cervical cancer (cases) and the remainder (100) were haven't got symptoms or signs of cervical cancer (control group). Primary data were collected using a questionnaire. Secondary sources of data related to the topic of the current study were books, previous researches, Internet, and other related published and non-published articles. The data collected were analyzed by using SPSS programme V. 12.0. Results: The findings revealed that cervical cancer and satisfaction by sexual education as well as sufficiency of the studied courses and importance of studying sexual education were significantly associated with cervical cancer (P < 0.05). Conclusion: This study was successful in raising awareness about the importance of sexual education as preventive means against STIs and cervical caner. The study highly recommends continuing sexual education and awareness campaigns among high risk group in the community.
- ItemAwareness of Sudanese Primary Health Care Workers about Oral Cancer(International Journal of Academic Pedagogical Research, 2021-08) Alkhair Abd Almahmoud Idris; Sakeena Mohammed Aldouma; Fatima Ali MohammedOral cancer is one of the 10 most frequent cancers worldwide; with about three-quarters of all cases occurring in the developing countries. Oral cancer is one of the major health problems in the Sudan, due to the habit use of Toombak which contain high level of the potent carcinogenic component of the tobacco. This study was aimed to assess the awareness of Sudanese primary health care workers about oral cancer. This descriptive cross sectional study was carried out in Khartoum State (Sudan).Questionnaires were filled with two hundred primary health care workers in Khartoum State, who were randomly selected included doctors, nurses, pharmacists, laboratory technologists, laboratory assistants and counters, assessed their knowledge about oral cancer. Analyses of data were carried out using the SPSS for windows software package. Our results revealed that most of respondents (52%) were at the prime of their youth [20-30 years] and (68.5%) had university education. There was gender differences among respondents, most of them were males constituted 64.5%, the majority (50%) had monthly income between 500-1000 which they were related to middle economic class. Most of respondents (54.5%) were tobacco users, (47%) were cigarette smokers, and among tobacco users majority of them (42%) were used it in between (7-10 years) and (42%) were used it only one time/day. Most of them (82%) were free of alcohol drink and Aragi had been the drink of choice to most of respondents constituted (42%). All respondents (100 %) had heard about oral cancer, Most of them (29%) got their knowledge of oral cancer from television, and majority of them (69%) choice tobacco as the major risk factor for oral cancer. Most of respondents (27%) mentioned that swelling in mouth is the most important signs of oral cancer, and (33%) choice bleeding in mouth as the most important symptoms of oral cancer. Most of respondents (45%) said that histological technique (examination of surgical biopsy) is the best method for diagnosis, and (42%) preferred chemotherapy as the best method for treatment. Majority of respondents (53%) considered stop using of tobacco and early diagnosis as the best method for prevention of oral cancer. In conclusion our results revealed that primary health workers in Khartoum State (Sudan) had a good knowledge about oral cancer risk factors, signs, symptoms, diagnostic techniques and prevention methods but they had poor knowledge about the best treatment methods of oral cancer.
- ItemCytomorphological Pattern of Urine among Sudanese Patients with Urinary Tract Stone in Shendi Locality(International Journal of Academic Multidisciplinary Research, 2021-09) Mohammed Abdelgader Elsheikh Mohammed; Mahmoud Ibrahim Osman HamadKhalfalla; Alkhair Abd Almahmoud Idris; Rayan Jaffer Mohammed Khalfalla; Samia Abduelaziz Hassan Bashir; Adan Tagaldeen Ahmed Almsaadd; TasneemMutasimYousifFedlemolaBackground: Urinary calculi can induce urothelial cellular abnormalities comparable with those of malignancy. Aim: To detect the Cytomorphological Pattern of Urine in Patients with Urinary Tract Stone among Sudanese patients in Shendi Locality. Materials and methods: This was descriptive cross-sectional study conducted in Shendi locality –River Nile State-Sudan, samples were collected from different blocks. Then the collected samples were transferred to Histopathology lab where they processed and stained. A questionnaire for collection demographic data was performed with every participant. Results: The cytological changes in voided urines were analysed from cases and controls, 35 urine samples were taken from each group. Cytological changes were detected in (25/35) 71.4% among cases, and (0/35) 0.00% in controls. No malignancy was seen in all samples. Dyskaryosis in urine cytology revealed that, (12/35) 34.2% of cases with dyskaryosis, while no sample of controls contain dyskaryosis. Cellular atypia was detected in (19/35) 54.2% in the cases and 0/35 0.00% in controls. Metaplasia was detected in (19/35) 54.2% in cases and 0/35 (0.00%) in controls. Features of urinary tract infection were detected in (17/35) 48.5 % in cases and (3/35) 8.57% in controls. Chronic Inflammation conditions were detected in (14/35) 40% of case, (1/35) 2.85% of controls, while acute inflammation present in (8/35) 22.8% of cases and (1/35)2.85%.of controls.Conclusion: Urinary tract stone are more common in peoples live in Shendi town than people's lives in surrounding areas and Metaplasia is the most common cytological changes.
- ItemEvaluation of the Effect of Three Local Methods on Treatment of Contaminated Water in Rural Area in Sudan(International Journal of Academic Multidisciplinary Research, 2021-08) Nazar Abdelaziz El Nasri; Alkhair Abd Almahmoud Idris; Reem Hassan Hussein; Shahinaz IbrahimElnaimWater contamination was playing a major role in the health hazards. Scientific verification for some natural methods used to treat water is still limited. Aim: This laboratory based study aimed to evaluate the effect of Broad bean seed (vicia faba), Fenugreek seed (Trigonela foenum gracium) and Zir in treatment of contaminated water. Materials and methods: One sample of water from Gabarona Camp in West Omdurman was examined for Physical, Chemical and microbial parameters before and after treatment with Broad bean seed, Fenugreek seed and stored in Zir in different duration of times for 5, 10,15,30,45 and 60 minutes . Results: The addition of Fenugreek, Broad bean seeds and storage in Zir lead to partially reduction of Physical characteristics of water. The results of chemical analysis of GWTBB, GWTF and GWTZ, showed that total dissolved salts (TDS) were ranged from (520-900 mg/l). After treatment with the Fenugreek, Broad bean and Zir the level of Total hardness was improved to minimum of 50, 45, and 48 at 60 min respectively. The reduction in total hardness and total dissolve salts for GWBB, GWTF and GWTZ was found to be statically differences (p≤0.05). The addition of Broad bean and storage in Zir reduced water fluoride content at 5 min to 1.3 mg/l, 1.5 mg/l. respectively. While treated water using Fenugreek exhibited lower reduction from 1.7 mg/l to 1.3 mg/l at 60 minutes. The MPN of untreated water sample was (440). The results indicate a reduction in the microbial load in GWTF, GWTBB and GWTZ by increased time duration of treatments. Our results showed that these common local methods for treatment of water slightly reduced the microbial, chemical and physical contamination of water.
- ItemImmunoexpression of Vascular Endothelial Growth Factor among Sudanese Patients with Bladder Cancer(International Journal of Academic Health and Medical Research, 2021-09) Changjowk Peter Lai AKER; Mohammed Abdelgader Elsheikh MOHAMMED; Elsadig Ahmed ADAM; Alkhair Abd Almahmoud IdrisVascular endothelial growth factor (VEGF) is a signaling protein which is important for formation of the circulatory system and growth of blood vessels from pre-existing vasculature. Cancers that can express VEGF are able to grow and metastasize, because many solid cancers require an adequate blood supply to grow beyond the limited size. Aim: To determine the Immunoexpression of Vascular Endothelial Growth Factor among Sudanese Patients with Bladder Cancer. METHODOLOGY: This was an analytical cross-sectional study, included forty patients with (TCC); study patients from different Histopathology laboratories in Khartoum state- Sudan, VEGF was detected by using IHC method. RESULTS: VEGF immunoexpression was reported positive in 20 out of 40 patients (50%), the study conducted that; there was an association of VEGF immunoexpression and higher tumor grade of (TCC) as the frequency of VEGF expression was 16 out of 27 patients (59.2%) with high grade, while the frequency of VEGF expression was 4 out of 13 patients of low grade (30.8%) P value = 0.010. CONCLUSSION: according to obtained results we concluded that; the, there was a significant association between VEGF and bad prognosis of (TCC).
- ItemThe expression of Vascular Endothelial Growth Factor (VEGF) and Ki67 in Correlation to Stage of Breast Cancer(International Journal of Academic Multidisciplinary Research, 2021-08) Mohammed Ismail Idreis Adam; Alkhair Abd Almahmoud Idris; Mohamed Abdelgader ElsheikhBreast cancer (BC) is a common malignant neoplasm comprising a large heterogeneous group of cancers with variable histological type, biological and clinical characteristics. Aim: This study was aimed to detect over expression of vascular endothelial growth factor and Ki67 in correlation to stage of breast cancer. Materials and Methods: This was descriptive cross sectional hospital based study conducted in Radiation &Isotopes –Center of Khartoum (RICK). Included Sudanese women with breast cancer during the period between (October 2020 To January 2021). Purposive sampling techniques was used in this study included 50 subject, from each tissue sample paraffin block was prepared two paraffin sections it was cut into 3μm thickness section floated into preheated floating water bath at 40˚c, two sections were placed in coated glass slide for Immunohistochemistry, one section was placed in clean microscopical slide for Hematoxylin and Eosin , incubated in oven at 58˚c. Results: The study results revealed that expression of VEGF in invasive ductal carcinoma was showed positive staining reaction in 14 cases (28%). No expression of VEGF was reported in 4 cases of stage I, in 7 out of 32 cases of stage II, and in all 7 cases out of 7 of stage III .There was significant positive correlation between VEGF expression and the stage of tumor (p value <0.000), and a higher proportion of cases were found in stage II and III. There was significant positive correlation between VEGF expression and Ki67(p value <0.000). Conclusion: This study concluded that there was relationship between VEGF expression and cancer stage and Ki67 expression. Recommendations: The study recommends that further study with more sample size is required.
- ItemThe Role of Cytological Methods in Evaluate Urine of Sudanese Patients with Renal Failure(International Journal of Academic Health and Medical Research, 2021-08) Enas Jafar Yousif; Hadeel Hatim Mubarak; Alia Abdelrahman Eshag; Alkhair Abd Almahmoud IdrisRenal failure is a major health problem in Sudan and each year the number of patients is increasing. Aim: To determine the cytological changes of urinary tract cells among patients suffering from renal failure. Materials and methods: This was descriptive laboratory based study conducted in Khartoum State. A random sample of 85 urine samples were taken from (all ages and both sexes) patients with renal failure lives in Khartoum; the remaining 35 samples was taken from health population as control. Questionnaire containing essential patient identification data was used. Results and discussion: Statistical analysis showed that there was significant statistical association between age, gender, medical history of chronic disease and type of renal failure (acute or chronic) to chronic changes in urinary tract cytology in terms of bacterial, Candida, Trichomonas infections (P-value < 0.05). Conclusion: We conclude that our study highlighted the role of urine cytology as screening tool for patients with renal failure as adjusted method to other clinical investigations. The inflammation and infection, bacterial, parasitic or fungal are the most common.