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- ItemPrevalence of Vancomycin Resistance Staphylococcus aureus in Khartoum -Sudan(Napata College, 2020)Background: This study conducted to detect Vancomycin resistance Staphylococcus aureus in patients with different clinical manifestations in Sudan - Khartoum state. From October 2020. A bio let Cross sectional study were done, (100) samples from different clinical isolates (Urine, Wound, semen and nasal swab) all samples were randomly selected, demographic data was recorded for each sample include age, gender and antibiotic administration. Material and method: All samples were confirmed by Gram stain, biochemical tests. Overall, 100 samples (77) male, (33) female, age range (19-37) years were included in this study. Result: The antimicrobial susceptibility of the isolates was determined using Kerpy –Bour disk diffusion method. result showed Staphylococcus aureus sensitive for77%, 22% showed intermediate and 1% for vancomycin resistant, this only sample was isolated from female urine culture, intermediate present in 10 females ,12 in male while sensitive 22 female and 65 male. Conclusion: The result of this study confirm that the Vancomycin is the drug of choice until far So that the situation continues as it is to avoid resistance , 22% intermediate these percentage borderline show sign and alarm to educate population ,should follow the antibiotic administration policies and avoid (misuse and overdose) and Susceptibility test must be done for clinical isolate to avoid antimicrobial drug resistance (ADR).
- ItemPrevalence of hepatitis B virus among donors in Khartoum hospitals(Napata College, 2020)Background: The prevalence of transfusion associated hepatitis B virus infection across different geographical population. We sought to estimate prevalence of hepatitis B surface antigen among blood donors in Khartoum hospitals. Method: This was a retrospective study which involved reviewing of blood donation records for the year 2020, from Oct. to Dec. at Khartoum hospitals. The records were analyzed to determine the prevalence of hepatitis B virus among blood donors. Results: A total of (100) blood donors were collected from Oct. to Dec. 2020 according to Questionnaire and the analysis were show the prevalence of HBV, according to blood groups the positive group sample have higher valid percent than the Negative of group sample. According to the ages of groups, it ranged between (31-40) old, is represented the higher standard, with ratio of 54%. Conclusion: The findings suggest that the study region is of intermediate to high endemicity with hepatitis B infection. Planning more extensive screening and vaccination campaigns and educational programs would help reduce the transmission of the infection among the general people.
- ItemAssessment of Blood Urea, Creatinine, Uric Acid, Calcium and Phosphorus levels pre- and post-dialysis in Sudanese patients diagnosed with Chronic Kidney Disease (CKD).(Napata College, 2020)Background: Chronic Kidney Disease (CKD) is a permanent Loss of normal kidney functional or structural with or without reduction in Glomerular Filtration Rate (GFR), which may be due to various factors including infections, autoimmune diseases, diabetes, hypertension and other endocrine disorders, and toxin chemicals, may lead to death. Materials and Methods: A descriptive Cross-sectional study was conducted to measure the effectiveness of haemodialysis on (19) Sudanese patients with chronic kidney disease aged between (25-60). Three ml of venous blood was drawn pre and post dialysis from each patient, using disposable syringe. Serum Level of urea, creatinine, uric acid, calcium and phosphors were estimated in all samples by co-bas C311, statistical evaluation was performed using SPSS for windows. Results: The study showed significance statistical difference in the mean of urea, creatinine, uric acid and phosphorus p-value(0.000001),(0.0001),(0.0001),(0.002) respectively however the mean of calcium showed insignificant statistical difference p-value(0.992). Conclusion: The findings showed that hemodialysis have an effected on urea, creatinine, uric acid and phosphorus but has no effect on calcium.