Prevalence of Vancomycin Resistance Staphylococcus aureus in Khartoum -Sudan

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Alamen Elnel Alamen
Ahmed Abdullah Adam
Enas Awad Idrees
Badraldeen Mohammed Ahmed
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Napata College
Background: This study conducted to detect Vancomycin resistance Staphylococcus aureus in patients with different clinical manifestations in Sudan - Khartoum state. From October 2020. A bio let Cross sectional study were done, (100) samples from different clinical isolates (Urine, Wound, semen and nasal swab) all samples were randomly selected, demographic data was recorded for each sample include age, gender and antibiotic administration. Material and method: All samples were confirmed by Gram stain, biochemical tests. Overall, 100 samples (77) male, (33) female, age range (19-37) years were included in this study. Result: The antimicrobial susceptibility of the isolates was determined using Kerpy –Bour disk diffusion method. result showed Staphylococcus aureus sensitive for77%, 22% showed intermediate and 1% for vancomycin resistant, this only sample was isolated from female urine culture, intermediate present in 10 females ,12 in male while sensitive 22 female and 65 male. Conclusion: The result of this study confirm that the Vancomycin is the drug of choice until far So that the situation continues as it is to avoid resistance , 22% intermediate these percentage borderline show sign and alarm to educate population ,should follow the antibiotic administration policies and avoid (misuse and overdose) and Susceptibility test must be done for clinical isolate to avoid antimicrobial drug resistance (ADR).