Batch 3

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Browsing Batch 3 by Author "Abdalla Sayed Hamid Hamed"

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    MEASUREMENT OF COAGULATION PARAMETERS & D-DIMER AMONG SUDANESE PREGNANT WOMEN WITH PREECLAMPSIA IN KHARTOUM STATE IN 2022.
    (Napata College, 2022) Abdalrhman Adam Suliman Adam; Abdalla Sayed Hamid Hamed; Ahmed Ibrahim Khalil Mohamed; Rashed Ahmed Khalafallah Ali
    Background: Preeclampsia affects 5%–7% of all pregnancies globally and is the leading cause of maternal and fetal death and morbidity. The mechanisms responsible for the pathogenesis of preeclampsia are unclear. In this study we aimed to measure coagulation parameters and D-dimer level among Sudanese pregnant women with Preeclampsia. Patients and Methods: case control hospital-based study Conducted at Omdurman Military Hospital. Khartoum, Sudan, study include two groups s ixty were women healthy twenty and group Cases were eclampsia -pre with women and questionnaire, interviewing direct using collected data ،control as included were D.dimer and INR APTT, PT, patients. all from collected was sample blood .(26 vs) programe ware soft SPSS using analyzed Data assessed. Results: out of total over one third 31 (38.8%) of patients within age group 20-30 years, followed by 22(28.3%) within age group 31-40 years. No significant difference in age group between cases and controls. According to parity, 23(38.3 %) of cases were Primigravida, 20(33.3%) were multipara, and 17(28.3%) were Grand multipara. Compared to control group 12(60%) of control group were multipara. (P value= 0.00). There was significant difference in mean PT (cases 23.34±21.4, vs controls control:18.99±1.37), (P value=0.036). INR was significantly higher among cases group (1.17±0.18 vs 1.10±0.10), (P value =0.00). D. dimer was significantly higher among cases (mean±SD) (5595.4 ±2442.0 vs 3240.6± 724.6). There was Statistically insignificant differences in PT, APTT, and INR according to preeclampsia severity. (P value>0.05). D. dimer significantly incresed with severity of preeclampsia (P value =0.041). Conclusion: Prothrombin time, INR, and D. dimer were significantly higher among preeclampsia group, and increased with preeclampsia severity.