Determination PT and APTT in pregnant women in Khartoum during the period from June to October 2022.

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Minna Allah Mubarak
Nesreen Gaffer
Razaz Kamal
Safwan Mohamed ALmubark
Taif Abo Algassim
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Napata College
As a result of the typical physiological needs of pregnancy and childbirth, the hemostatic system develops a physiological hypercoagulable condition and the levels of coagulation factors I, VII, IX, X and XII rise during pregnancy. The aim of this study was to compare pregnant women to non-pregnant women in terms of coagulation changes during all three trimesters of pregnancy. The research was conducted 50 pregnant women, aged range between 20-39 year, who attended Dar ALelag Medical laboratory in Khartoum-Sudanduring the period from June 2022 to January 2023,followed undone for all 50 pregnant women during (first, second and third trimesters) by assigning PT,& PTT and compared with other 50 non-pregnant women which serve as controls. PT,& PPT showed decrease in third trimesters in pregnant women and PT also decrease in second trimester, while PTT decrease in all three trimesters in pregnant women when compared with non-pregnant women. These parameters also decrease in third trimester when compared with first trimester. In good, a condition of physiological low-grade intravascular coagulation characterizes normal pregnancy. In our research, in each trimester, there were alterations in the levels of coagulation parameters. In addition, the ranges for coagulation measures were supplied, which may help clinicians track coagulation in pregnant women more effectively.