Determine C-Reactive protein as a Biomarker For the severity of Bacteria Infections in Younger and Older Sudanese Patients

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Altayeb Gaffar Hamad Alnill Osman
Mohammed Alsheikh Alamin Alsheikh
Mustafa Mohammed Yousif Osman
Noon Ibrahim Musa Mohammed
Omar Mohammed Ahmed Alnour
Salih Badr-Aldin Yassin Bashir
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Napata College
Background :C-reactive protein (CRP) is frequently utilized in younger populations, although its efficacy in suspecting of bacterial infections in elderly populations is less clear. This study looked at the effectiveness of serum CRP levels in the suspecting of bacterial infections in elderly adults and younger patient at an early stage. Method :In a prospective cross-sectional study from July to September 2022, 50 serum and various samples were taken from patients at a private military hospital in Omdurman, Sudan, including blood, urine, wound swabs, throat swabs, and sputum. Cobas c 311 used the quantity method to measure the serum C-RP level and collect samples for culture and processing according to stander bacteriological techniques. Result :A total of 50 patients 27 male 54% and 23 female 46% were recruited over a period of 3 months with ratio of (1:1.7). CRP levels in patients less than 20 years show 56.5±50.8mg/l (mean±SD), in 20-40 years 100.7±66.5 mg/l (mean±SD), in 41-60 years show higher CRP level 124.87±81.8 mg/l (mean±SD), in More than 60 years 128.1±94.8 (P-value 0.467), higher CRP was found in Respiratory tract infection by Ps.aeruginose bacteria and we found no association between the result of C-RP and demographic data across the younger and older groups (Age group), also we conclude that there is no association between the result of C-RP and males and females (Sex group). Conclusion: In this study CRP level alone as biomarker indicator of inflammation and infection cannot use alone to suspect the type of bacterial infection, and there were no significant different in CRP level as response to bacterial infection in different patients ages and genders of patients.