Clinical and Laboratory Profile of Dengue Fever Among Patients Admitted to The Military Hospital, Omdurman, Sudan 2026
Clinical and Laboratory Profile of Dengue Fever Among Patients Admitted to The Military Hospital, Omdurman, Sudan 2026
No Thumbnail Available
Date
2026
Authors
Mabb Alsadeg Edres Mohammed
Mohammed Ibrahim Elshikh Mohammed
Rayan Ahmed Ali Omer
Nosiaba Altaher Hassan Alnazef
Alaa Merghani Keissan
Journal Title
Journal ISSN
Volume Title
Publisher
Napata College
Abstract
Background: Dengue fever is a significant global public health concern, with an estimated 3.9
billion people at risk across 128 countries. In Sudan, the disease is highly endemic, with a
national prevalence of approximately 27%. Despite its prevalence, early clinical diagnosis
remains challenging due to non-specific manifestations that overlap with other endemic febrile
illnesses like malaria, leading to potential delays in managing life-threatening complications.
Objective: To evaluate the clinical, epidemiological, and hematological profiles of laboratory
confirmed dengue patients at Omdurman Military Hospital to improve diagnostic accuracy and
clinical management.
Methodology: A retrospective hospital-based cross-sectional study was conducted at Omdurman
Military Hospital. The study population included all laboratory-confirmed pediatric and adult
dengue cases managed between September 2025 and December 2025. Data were extracted from
medical records using a structured checklist covering socio-demographic, clinical, and laboratory
parameters. Data analysis was performed using SPSS version 26.0.
Results: The study included 59 participants with a mean age of 39.46 \pm 14.77 years. The most
common clinical presentations were fever (94.9%), headache (93.2%), and myalgia (81.4%).
Epistaxis (40.7%) and bleeding gums (23.7%) were the leading hemorrhagic manifestations.
Hematological findings revealed a mean platelet count of 133,180.0 \pm 93,289.0 cells/mm³ and
a mean WBC count of 5,917.5 \pm 4,121.2 cells/mm³. Diagnoses were primarily confirmed via
IgM (96.6%) and NS1 antigen (88.1%). While 62.1% of cases were classified as classic Dengue
Fever, 37.9% developed severe forms (DHF and DSS). Notably, malaria co-infection was
present in 31.0% of patients.
Conclusion: Dengue fever is a major cause of acute febrile illness in Omdurman, primarily
affecting young and middle-aged adults. Although most outcomes were favorable (93.2%
discharge rate), the high prevalence of severe forms and malaria co-infection necessitates routine
hematological monitoring and integrated fever management protocols to ensure early detection
and prevent fatalities.
Description
Napata College