Pharmacy

Permanent URI for this community

http://dspace.napata.edu.sd/handle/123456789/48

Browse

Browsing Pharmacy by Author "Hazim abdalrhman osman salih"

Now showing 1 - 1 of 1
  • Item
    Essential Oil from Eucalyptus camaldulensis: GC MS Profile, Antimicrobial and Antioxidant Properties
    (Napata College, 2023) Alhadi Amir Ibrahim Ahmed; Almoiz mustafa hassan abdalla; Hazim abdalrhman osman salih; Nemat altayeb yousif mohammed
    Background: Natural plants as herbal remedies are being employed to prevent and cure several illnesses that vary in different community. Medicines had been explored from leaves, flowers and barks of plants. Continuous spread of infectious diseases is a major problem worldwide. Due to multiple and repeated issues with antibiotics efficacy, it became essential to evaluate biological properties of plants from different geographical origins. Eucalyptus camaldulensis (Family: Myrtaceae) leaves have been reported for various medicinal effects like antibacterial, anti-inflammatory, anti-viral, and anti-oxidant. Objectives: The objective of the present study is to determine the chemical composition and evaluation of two pharmacological activities; antimicrobial and antioxidant of E.camaldulensis essential oil. Methods: Essential oil was obtained by steam distillation method. And subjected to GC-MS to determine the active constituents. Antimicrobial activity applied with disc diffusion method whereas antioxidant activity was performed through DPPH assay. Result: GC-MS results of the pale yellow essential oil revealed a total of seventeen compounds which identified and representing 99.0% of the total oils. The major constituents of the oil were; Eucalyptol (34.15 %), P-Cymene (22.07%), (-) Globulol(9.14%),1H-Cycloprop[e]azulene, decahydro-1,1,7-trimethyl-4-m (8.17%), gamma.-Terpinene(5.60%). Antimicrobial activity against three pathogenic bacterial strains exhibited a good inhibition zone which ranged between 44 to 8mm at 12.5, 25 and50 30 μg/mL oil, whereas C. albicana obtained 40 to 12 at the same concentrations. The antioxidant activity demonstrated a weak activity (58±0.01) this inhibition is lower than that obtained by the standarad Propyl gallate (92±0.0). Conclusion: The important role that E.camaldulensis plant play in folk medicine has led us to develop this study in order to investigate the major pharmacological activities, so this plant can be used in future as a valuable source of pharmacologically active antioxidants and antimicrobial agents.