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A rare diagnostic case of angioimmunoblastic T-cell lymphoma
(Science Progress and Research, 2021-12-22) Mujahed Nooraldaem Mirghani Adam; Mohammed NooraldaemMirghani Adam; Alkhair Abd Almahmoud Idris; Ali Seedahmed Mohamed Ali; Ismail Osman Khalid
Angioimmunoblastic T-cell lymphoma is a malignancy of mature T-cells. A 45 years old Sudanese female with generalized lymphadenomegalyreferred from Tayba hospital to Al-tayseer reference medical centre in histopathology and cytology laboratory department (Sudan) for her lymph node histopathology analysis. A surgical lymph node biopsy for histopathology analysis stained by H&E was performed and sections showed effacement of normal architecture of lymph node with disappearance of follicles and germinal center composed of polymorphic infiltrate of small tumour cells and large tumour cells. The small tumour cells showed irregular nuclei and clear cytoplasm. In this case report, we state that the delay of diagnosis was mainly a consequence of an insufficient clinical history, which led to an incomplete histological analysis, delay of reporting and need for second opinions for interpretation.